Mirabegron 223673-61-8 Inhibitor Umqondiso we-Neuronal
Intlawulo:T/T, L/C
Imvelaphi yeMveliso:eTshayina
Indawo yokuthumela ngenqanawa:Beijing/Shanghai/Hangzhou
Umthamo wemveliso:100kg/ngenyanga
Umyalelo(MOQ):25kg
Ixesha lokukhokhela:Iintsuku zokusebenza ezi-3
Imeko yokugcina:Igcinwe kwindawo epholileyo, eyomileyo, ubushushu begumbi.
Ipakethe imathiriyeli:igubu
Ubungakanani bepakethi:25kg/igubu
Ulwazi ngokhuseleko:Ayizompahla eziyingozi
Intshayelelo
I-Mirabegron, i-beta-3 i-adrenergic receptor agonist, evuselela i-beta-3 adrenergic receptor kwaye iphumle i-detrusor muscle egudileyo, ngaloo ndlela ikhulise umthamo wesinye kwaye isetyenziselwa ukunyanga iimpawu ze-bladder esebenzayo (OAB), ezifana nokukhawuleza ukungazinzi, ukukhawuleza, kunye namaxesha.
Izibonelelo zayo zifana neyeza le-antimuscarinic ezifana ne-solifenacin okanye i-tolterodine.
Inkcazo (USP/EP)
Into | Inkcazo |
Imbonakalo | Mhlophe ukuya kumgubo omhlophe |
Ukuchongwa | IR, HPLC |
Isiqulatho samanzi | NMT 0.5% |
Intsalela ekutshisweni | NMT 0.1% |
Intsimbi enzima | NMT 20ppm |
Umxholo wePalladium | NMT 20ppm |
Isomer ye-Optical | NTM 0.5% |
Into enxulumeneyo | Z-168*: NMT 0.15% |
SC03610*: NMT 0.15% | |
Nakuphi na okunye ukungcola okungaziwayo: NMT 0.10% | |
Ukungacoceki kukonke: NMT 0.5% | |
I-2-(2-aminothianzol-4-yl) i-acetic acid | NMT 0.1% |
Isinyibilikisi esishiyekileyo | IMethanol: NMT 0.3% |
I-Ethyl acetate: NMT 0.5% | |
THF: NMT 0.072% | |
I-Benzene: NMT 0.0002% | |
Itoluene: NMT 0.089% | |
Isivavanyi | 98.0% - 102.0% |
PSD | D (0.5): 10μm - 30μm |
D (0.9): 20μm - 80μm |