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Imveliso

I-Atipamezole HCL 104075-48-1 Antipyretic-analgesic

Inkcazelo emfutshane:

Izithethantonye:IAtipamezole hydrochloride, 4-(2-Ethyl-2-indanyl) imidazole hydrochloride
Inombolo yeCAS: 104075-48-1

Inombolo yeCAS:104075-48-1

Umgangatho:Endlini

Ifomula yemolekyuli:I-C14H16N2.HCl

Ubunzima beFomula:248.75


Iinkcukacha zeMveliso

Iithegi zeMveliso

Intlawulo:T/T, L/C
Imvelaphi yeMveliso:eTshayina
Indawo yokuthumela ngenqanawa:Beijing/Shanghai/Hangzhou
Umthamo wemveliso:100kg/ngenyanga
Umyalelo(MOQ):25kg
Ixesha lokukhokhela:Iintsuku zokusebenza ezi-3
Imeko yokugcina:Igcinwe kwindawo epholileyo, eyomileyo, ubushushu begumbi
Ipakethe imathiriyeli:igubu
Ubungakanani bepakethi:25kg/igubu
Ulwazi ngokhuseleko:Ayizompahla eziyingozi

I-Atipamezole HCL

Intshayelelo

I-Atipamezole hydrochloride, igama lekhemikhali: 4- (2-ethyl-2-indan) imidazole hydrochloride.I-Atipamezole hydrochloride ngokukhuphisanayo inqanda i-alpha 2 i-adrenergic receptors, kwaye i-alpha2 i-adrenergic receptor blocker esebenzayo, ekhethayo kunye nokhuphiswano inqanda i-α2 i-adrenergic receptors.

Imiphumo yayo ye-pharmacological kukunciphisa i-sedation, ukunciphisa uxinzelelo lwegazi, ukunyusa ukubetha kwentliziyo kunye nesantya sokuphefumula, kunye nokunciphisa imiphumo ye-analgesic ye-α2-adrenoceptor blockers, eyona nto isetyenziselwa ukubuyiswa kwe-anesthesia emva kokuhlinzwa kwizilwanyana.

Inkcazo (kwimigangatho yendlu)

Into

Inkcazo

Imbonakalo Okumhlophe okuqinileyo
Ukuchongwa IR
Ukuchongwa kweekloridi Ukuthelekisa ukuma
Indawo yokunyibilika 211℃-215℃
Ukungcola ngokupheleleyo ≤ 0.1%
Ukungafezeki komntu ≤0.05%
Ilahleko ekomisweni ≤0.05%2hrs kwi-105℃
Uthuthu olufakwe emanzini 0.05% ubukhulu
Ph yesisombululo esisemgangathweni 5-6
Isisombululo(1% isinyibiliko emanzini) engenambala
Iintsimbi eziNzima zizonke

(NjengePb Cd Cr Ni)

≤20ppm
Izinyibilikisi ezishiyekileyo I-acetone <5000ppm
Methylbenzene<890ppm
Thf <720ppm
I-Methanol <3000ppm
Dichloromethane<600ppm
I-Ethyl acetate<5000ppm
N-hexane<290ppm
Ethyl utywala <5000ppm
Ubunyulu (HPLC) ≥99%

Inkcazo Ibakala lokutofa

Into

Inkcazo

Imbonakalo Umgubo omthubi ukuya kweorenji awunavumba.
Ukuchongwa IR, HPLC

Intsalela ekutshisweni

≤0.5%

Izinto ezinxulumeneyo

Kwi303nm

I-Amphotericin A ≤2.0%

Ukungcola okungaziwayo komntu ≤1.0%

Kwi383nm

I-Amphotericin X1 ≤4.0%

Ukungcola okungaziwayo komntu ≤2.0%

Ukungcola okupheleleyo

≤15.0%

Izinyibilikisi ezishiyekileyo

Iacetone ≤0.5%

IMethanol ≤0.3%

Umda weMicrobiological

Ubalo lweAerobic microbial ≤1000cfu/g

Ukungunda kunye negwele ≤100cfu/g

Escherichia coli Ukungabikho kwi-1g

I-endotoxins yebhaktheriya

<1.0EU/mg

Isivavanyi

≥850 i-amphotericin B iiyunithi / mg, ezibalwe kwisiseko esomileyo


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