I-Ursodeoxycholic acid 128-13-2 Inkqubo yokugaya ukutya kweCholagogic
Intlawulo:T/T, L/C
Imvelaphi yeMveliso:eTshayina
Indawo yokuthumela ngenqanawa:Beijing/Shanghai/Hangzhou
Umthamo wemveliso:2000kg/ngenyanga
Umyalelo(MOQ):25kg
Ixesha lokukhokhela:Iintsuku zokusebenza ezi-3
Imeko yokugcina:Igcinwe kwindawo epholileyo, eyomileyo, ubushushu begumbi.
Ipakethe imathiriyeli:igubu
Ubungakanani bepakethi:25kg/igubu
Ulwazi ngokhuseleko:Ayizompahla eziyingozi
Intshayelelo
I-Ursodeoxycholic acid (UDCA), ekwabizwa ngokuba yi-ursodiol, yi-asidi ye-bile yesibini, eveliswa ebantwini kunye noninzi lwezinye iintlobo ze-metabolism yibhaktheriya yamathumbu.Idityaniswe esibindini kwezinye iintlobo, kwaye yaqala ukuchongwa kwi-bile yebhere, ephuma kwigama layo elithi Ursus.Kwifom ecocekileyo, isetyenziswe ukunyanga okanye ukukhusela izifo ezininzi zesibindi okanye i-bile ducts.
I-UDCA isetyenziswe njengonyango lwezonyango kwi-gallstone disease (cholelithiasis) kunye nodaka lwe-biliary.I-UDCA inceda ekunciphiseni i-cholesterol saturation yenyongo kwaye ikhokelela ekunyibilikeni kancinci kwe-cholesterol etyebileyo kwi-gallstones.
I-UDCA inokunikwa emva kotyando lwe-bariatric ukunqanda i-cholelithiasis, edla ngokwenzeka ngenxa yokuncipha ngokukhawuleza kobunzima obuvelisa i-biliary cholesterol oversaturation kunye ne-biliary dyskinesia utshintsho lwehomoni yesibini.
Iinkcukacha (EP10)
| Into | Inkcazo |
| Imbonakalo | Umgubo omhlophe okanye phantse omhlophe |
| Ukunyibilika | Ayinyibiliki ngokupheleleyo emanzini, inyibilika ngokukhululekileyo kwi-ethanol (96%), inyibilika kancinane kwi-acetone, ayinyibiliki kwi-methylene chloride. |
| Indawo yokunyibilika | 202-204℃ |
| Ukuchongwa | I-spectrum ye-IR efanayo ne-ursodeoxycholic acid CRS |
| Indawo ephambili kwichromatogram efunyenwe ngesisombululo sovavanyo (b) iyafana kwindawo, umbala kunye nobukhulu kwindawo yomgaqo kwichromatogram efunyenwe ngesisombululo sereferensi (a). | |
| Ukumiswa okufunyenweyo kuluhlaza-blue. | |
| Ukujikeleza okuthe ngqo | +58.0 ~ + 62.0 ° |
| Ukungcola C | I-Lithocholic acid ≤ 0.1% |
| Izinto eziyeleleneyo (HPLC) | ukungcola A: i-chenodeoxycholic acid ≤ 1.0% |
| ukungcola okungachazwanga ≤ 0.1% | |
| iyonke ≤ 1.5% | |
| Iintsimbi ezinzima | ICH Q3D |
| Ilahleko ekomisweni | ≤ 1.0% |
| Uthuthu lwesulphate | ≤ 0.1% |
| Isivavanyi | 99.0%~101% (Into eyomileyo) |
| Izinyibilikisi ezishiyekileyo | I-acetone ≤ 5000 ppm I-Ethyl acetate ≤ 5000 ppm Isopropanol ≤ 5000 ppm I-Ethanol ≤ 5000 ppm |
| Iimvavanyo zeMicrobiological | Ubalo olupheleleyo lwe-aerobic microbial ≤ 10³CFU/g Iyonke igwele kunye nokungunda kubalwa ≤ 10²CFU/g I-Escherichia coli: Ayikho kwi-1 g I-Salmonella: Ayikho kwi-10 g |
| Iipropati ezongezelelweyo | |
| Ukuhanjiswa kobungakanani besuntswana | I-100% yokupasa inombolo ye-180 yesihluzo (i-100% idlule i-80 mesh sieve) |
