I-Atipamezole HCL 104075-48-1 Antipyretic-analgesic
Intlawulo:T/T, L/C
Imvelaphi yeMveliso:eTshayina
Indawo yokuthumela ngenqanawa:Beijing/Shanghai/Hangzhou
Umthamo wemveliso:100kg/ngenyanga
Umyalelo(MOQ):25kg
Ixesha lokukhokhela:Iintsuku zokusebenza ezi-3
Imeko yokugcina:Igcinwe kwindawo epholileyo, eyomileyo, ubushushu begumbi
Ipakethe imathiriyeli:igubu
Ubungakanani bepakethi:25kg/igubu
Ulwazi ngokhuseleko:Ayizompahla eziyingozi
Intshayelelo
I-Atipamezole hydrochloride, igama lekhemikhali: 4- (2-ethyl-2-indan) imidazole hydrochloride.I-Atipamezole hydrochloride ngokukhuphisanayo inqanda i-alpha 2 i-adrenergic receptors, kwaye i-alpha2 i-adrenergic receptor blocker esebenzayo, ekhethayo kunye nokhuphiswano inqanda i-α2 i-adrenergic receptors.
Imiphumo yayo ye-pharmacological kukunciphisa i-sedation, ukunciphisa uxinzelelo lwegazi, ukunyusa ukubetha kwentliziyo kunye nesantya sokuphefumula, kunye nokunciphisa imiphumo ye-analgesic ye-α2-adrenoceptor blockers, eyona nto isetyenziselwa ukubuyiswa kwe-anesthesia emva kokuhlinzwa kwizilwanyana.
Inkcazo (kwimigangatho yendlu)
Into | Inkcazo |
Imbonakalo | Okumhlophe okuqinileyo |
Ukuchongwa | IR |
Ukuchongwa kweekloridi | Ukuthelekisa ukuma |
Indawo yokunyibilika | 211℃-215℃ |
Ukungcola ngokupheleleyo | ≤ 0.1% |
Ukungafezeki komntu | ≤0.05% |
Ilahleko ekomisweni | ≤0.05%2hrs kwi-105℃ |
Uthuthu olufakwe emanzini | 0.05% ubukhulu |
Ph yesisombululo esisemgangathweni | 5-6 |
Isisombululo(1% isinyibiliko emanzini) | engenambala |
Iintsimbi eziNzima zizonke (NjengePb Cd Cr Ni) | ≤20ppm |
Izinyibilikisi ezishiyekileyo | I-acetone <5000ppm |
Methylbenzene<890ppm | |
Thf <720ppm | |
I-Methanol <3000ppm | |
Dichloromethane<600ppm | |
I-Ethyl acetate<5000ppm | |
N-hexane<290ppm | |
Ethyl utywala <5000ppm | |
Ubunyulu (HPLC) | ≥99% |
Inkcazo Ibakala lokutofa
Into | Inkcazo |
Imbonakalo | Umgubo omthubi ukuya kweorenji awunavumba. |
Ukuchongwa | IR, HPLC |
Intsalela ekutshisweni | ≤0.5% |
Izinto ezinxulumeneyo | |
Kwi303nm | I-Amphotericin A ≤2.0% |
Ukungcola okungaziwayo komntu ≤1.0% | |
Kwi383nm | I-Amphotericin X1 ≤4.0% |
Ukungcola okungaziwayo komntu ≤2.0% | |
Ukungcola okupheleleyo | ≤15.0% |
Izinyibilikisi ezishiyekileyo | Iacetone ≤0.5% |
IMethanol ≤0.3% | |
Umda weMicrobiological | Ubalo lweAerobic microbial ≤1000cfu/g |
Ukungunda kunye negwele ≤100cfu/g | |
Escherichia coli Ukungabikho kwi-1g | |
I-endotoxins yebhaktheriya | <1.0EU/mg |
Isivavanyi | ≥850 i-amphotericin B iiyunithi / mg, ezibalwe kwisiseko esomileyo |