Posaconazole 171228-49-2 Antibiotic
Intlawulo:T/T, L/C
Imvelaphi yeMveliso:eTshayina
Indawo yokuthumela ngenqanawa:Beijing/Shanghai/Hangzhou
Umthamo wemveliso:20kg/ngenyanga
Umyalelo(MOQ):10g
Ixesha lokukhokhela:Iintsuku zokusebenza ezi-3
Imeko yokugcina:Igcinwe kwindawo epholileyo, eyomileyo, ubushushu begumbi.
Ipakethe imathiriyeli:ingqayi
Ubungakanani bepakethi:10g/ibhodlela
Ulwazi ngokhuseleko:Ayizompahla eziyingozi
Intshayelelo
I-Posaconazole liyeza le-antifungal le-triazole.
IPosaconazole isetyenziselwa ukunyanga iAspergillus kunye nosulelo lweCandida.Ikwasetyenziselwa unyango lwe-oropharyngeal candidiasis (OPC), kuquka i-OPC refractory kwi-itraconzaole kunye / okanye unyango lwe-fluconazole.
Ikwasetyenziselwa ukunyanga usulelo oluhlaselayo lweCandida, Mucor, kunye neentlobo ze-Aspergillus kwizigulana ezibuthathaka kakhulu.
Inkcazo (kwimigangatho yendlu)
| Into | Inkcazo |
| Imbonakalo | Imhlophe okanye iphantse imhlophe, i-hygroscopic powder |
| Into | Inkcazo |
| Imbonakalo | I-crystalline powder emhlophe okanye emhlophe |
| Ukujikeleza okuthe ngqo | -28.0 ° ~ -34.0 ° |
| Ifom yeCrystal | Kufuneka ibe crystalline Ⅰ, kunye nee-engile ze-2-theta ze 14.4±0.2°,19.2±0.2°,21.7±0.2°,24.3±0.2°29.3±0.2° |
| Ukuchongwa | IR, HPLC |
| Izinto ezinxulumeneyo I | PO-R1 NMT 0.10% |
| PO-R2 NMT 0.10% | |
| PO-R3 NMT 0.10% | |
| PO-R4 NMT 0.10% | |
| PO-D3 & PO-D5 NMT 0.10% | |
| PO-D7 & PO-D10 NMT 0.10% | |
| Ukungcola ngakunye okungachazwanga NMT 0.10% | |
| Ubumdaka bubonke i-NMT 0.5% | |
| Izinto ezinxulumeneyo Ⅱ | PO-E NMT 0.10% |
| PO-D1 NMT 0.10% | |
| PO-R5 NMT 0.10% | |
| Izinyibilikisi ezishiyekileyo | I-Methanol NMT 3000ppm |
| I-Ethanol NMT 5000ppm | |
| Dichloromethane NMT 600ppm | |
| Tetrahydrofuran NMT 720ppm | |
| N, N-dimethyl formamide NMT 880ppm | |
| I-Triethylamine NMT 100ppm | |
| I-Dimethy sulfoxide NMT 5000ppm | |
| Amanzi | NMT 2.0% |
| Intsalela ekutshisweni | NMT 0.1% |
| Iintsimbi ezinzima | NMT 10ppm |
| Umda weMicrobial | Iyonke i-NMT ye-aerobic 1000cfu/g Iyonke igwele kunye nokungunda i-NMT 100cfu/g I-E.coli kufuneka ingabikho |
| Isivavanyi | 98.0% -102.0%(kwisiseko se-anhydrous) |
| 98.0% -102.0%(kwi-anhydrous kunye nezinyibilikisi simahla) |
