Iityhubhu zeLebhu

Imveliso

Fluralaner 864731-61-3 Organochlorine pesticides Anti-Parasitics

Inkcazelo emfutshane:

Izithethantonye:4-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methyl-N-(2-oxo-2-(2,2,2- trifluoroethylamino)ethyl)benzamide

Inombolo yeCAS:864731-61-3

Umgangatho:endlwini

Ifomula yemolekyuli:I-C22H17Cl2F6N3O3

Ubunzima beFomula:556.29


Iinkcukacha zeMveliso

Iithegi zeMveliso

Intlawulo:T/T, L/C
Imvelaphi yeMveliso:eTshayina
Indawo yokuthumela ngenqanawa:Beijing/Shanghai/Hangzhou
Umthamo wemveliso:2kg/ngenyanga
Umyalelo(MOQ):1g
Ixesha lokukhokhela:Iintsuku zokusebenza ezi-3
Imeko yokugcina:Igcinwe kwindawo epholileyo, eyomileyo, ubushushu begumbi.
Ipakethe imathiriyeli:ibhotile, ibhotile
Ubungakanani bepakethi:1g/ibhodlela, 5/ibhotile, 10g/ibhotile, 50g/ibhotile, 500g/ibhotile
Ulwazi ngokhuseleko:Ayizompahla eziyingozi

Fluralaner

Intshayelelo

I-Fluralaner sisitshabalalisi esicwangcisiweyo kunye ne-acaricide elawulwa ngomlomo okanye ngezihloko.

I-Fluralaner inqanda i-γ-aminobutyric acid (GABA) -i-gated chloride channels (i-GABAA receptors) kunye ne-L-glutamate-gated chloride channels (GluCls).Amandla e-fluralaner athelekiswa nefipronil.

Sisibulali zinambuzane esibanzi esinemisebenzi elungileyo yokubulala iintakumba, iintwala, i-hemiptera kunye ne-diptera, kwaye ubungangamsha bayo bungaphezulu okanye buthelekiseka naleyo yezinambuzane ezisetyenziswa ngokuqhelekileyo.

Ngokwekliniki ibonisa ukuba iFluralaner inokubonelela ngeeveki ezili-12 zokhuseleko lwexesha elide kwizinja kwi-antibody ectoparasite effect.Kulula ngakumbi kwaye kusebenza kuzo zombini izilwanyana zasekhaya kunye nezilwanyana zasekhaya.

Inokukhupha kwaye ibulale iintakumba kwizinja.Inokuthi isebenze ngokukhawuleza kwiintakumba zabantu abadala kwaye ihlale ixesha elide.Kwakhona kunokuthintela iintakumba ekungeneni kwamaqanda, ngaloo ndlela zitshabalalisa umjikelo wobomi beentakumba.Ezi zifuywa eziqhelekileyo ze-pet ectoparasites zifunxa isondlo sezilwanyana, kwaye ziyakwazi ukusasaza izifo ezininzi, ezinjengeembungu ezitshisiweyo, isifo seLyme, i-encephalitis yamahlathi, njl. Akuyi kuchaphazela kuphela ukukhula kunye nempilo yezilwanyana ezifuywayo, kodwa kwakhona kuzisa ingozi yempilo enokubakho kubanikazi bezilwanyana.I-Fluralaner ayinamsebenzi kwi-receptors ye-nervous ye-mammalian, ngoko ikhuselekile kakhulu kwizilwanyana ezincancisayo.

I-Fluralaner iphantse yabola zizilwanyana ezincinci.Ifom ye-molecular yasekuqaleni malunga ne-90-100% ikhutshwe ngeefeces ngaphandle kwe-metabolites.Phantse akukho kukhutshwa kwezintso, ukhuseleko oluhle kakhulu, akukho monakalo kwisibindi kunye nezintso zezilwanyana ezincinci.

Ayinalwazi lwaziwayo lokunganyangeki kumachiza kunye nemithetho yokuhambelana neziyobisi, kwaye ayixhathisi ngokufanayo kumayeza okubulala izinambuzane.Emva kokulawulwa komlomo, iyeza lisasazwa ngokulinganayo kumphezulu womzimba.Ithatha i-2 iiyure emva kokulawulwa komlomo.Emva kweeyure ze-4, inokubulala ubuncinane i-80% yezinambuzane.Ixesha lokukhusela lingafikelela kwiiveki ezili-12.Usulelo oluphindaphindiweyo lunakho ukufikelela kwisiphumo esihle kakhulu sokugxotha izinambuzane.Luhlobo lwechiza le-antibody ectoparasite enokhuseleko oluphezulu, olufaneleke kakhulu ukuba lusetyenziswe.

Inkcazo (kwimigangatho yendlu)

Into

Inkcazo

Imbonakalo

Umgubo omhlophe okanye omhlophe

Ukunyibilika

Inyibilika kwi-methanol

Ukuchongwa

Idatha ye-HNMR kunye ne-LCMS ihambelana nesakhiwo sekhemikhali.

Ukufuma

Akukho ngaphezu kwe-1.00%

Indawo yokunyibilika

176-178℃

Ukungcola okusisiseko (Pd)

≤10ppm (ICP-MS)

PSD

—-

Ukungcola ngokupheleleyo (HPLC)

Akukho ngaphezu kwe-1.00%

Ubunyulu (HPLC)

Ukubalwa komxholo wento engenamanzi iphakathi kwe-98 ~ 100%


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